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Post-Doctoral Associate - Chemical and Biochemical - Saint Paul Minnesota
Company: University of Minnesota Location: Saint Paul, Minnesota
Posted On: 04/17/2024
Apply for JobJob ID355445 LocationTwin Cities Job FamilyAcademic Full/Part TimeFull-Time Regular/TemporaryRegular Job Code9546 Employee ClassAcad Prof and Admin Add to Favorite JobsEmail this Job About the Job Postdoctoral Position in Cancer Prevention Research Using Chemical and Biochemical ApproachesStephen S. Hecht's laboratory in the Carcinogenesis and Chemoprevention Program, Masonic Cancer Center, University of Minnesota, has a postdoctoral position available, starting this spring or summer, for approximately 2 years. The laboratory is housed in the modern Cancer and Cardiovascular Research Building and focuses on mechanisms and prevention of cancer induced by environmental agents and tobacco products. All projects use rigorous chemical and biochemical approaches to identify and quantify specific metabolites and DNA damage products. Analyses are frequently based on structure determination and analytical quantitation by mass spectrometric methods in a modern multi-instrument facility next to the laboratory. Some recent publications are listed here:Cheng, G., Guo, J., Carmella, S.G., Lindgren, B., Ikuemonisan, J., Jensen, J., Hatsukami, D.K., Balbo, S., and Hecht, S.S. Increased acrolein-DNA adducts in buccal brushings of e-cigarette users. Carcinogenesis 43: 437-444 doi:10.1093/carcin/bgac026, 2022.Chen, M., Carmella, S.G., Lindgren, B.R., Luo, X., Ikuemonisan, J., Niesen, B., Thomson, N.M., Murphy, S.E., Hatsukami, D.K., and Hecht, S.S. Increased levels of the acrolein metabolite 3-hydroxypropyl mercapturic acid in the urine of e-cigarette users. Chem. Res. Toxicol. doi: 10.1021 acs.chemrestox.2c00145, 2022.Park, S.L., Le Marchand, L., Cheng, G., Balbo, S., Chen, M., Carmella, S.G., Thomson, N.M., Lee, Y., Patel, Y.M., Stram, D.O., Jensen, J., Hatsukami, D.K., Murphy, S.E., and Hecht, S.S. Quantitation of DNA adducts resulting from acrolein exposure and lipid peroxidation in oral cells of cigarette smokers from three racial/ethnic groups with differing risks for lung cancer. Chem. Res. Toxicol. doi: 10.1021 acs.chemrestox.2c00171, 2022. Li, Y. and Hecht, S.S. Mass spectrometric quantitation of N'-nitrosonornicotine-1-N-oxide in the urine of cigarette smokers and smokeless tobacco users. Chem. Res. Toxicol. 35: 1579-1588 doi: 10.1021/acs.chemrestox.2c00195, 2022.Responsibilities:This position involves approximately 80% laboratory research (wet chemistry sample analysis, mass spectrometry, etc.) and 20% compiling and reporting of results for publication. Qualifications All required qualifications must be documented on application materials. Minimum qualifications: Ph.D. in analytical chemistry, biochemistry, organic chemistry, or closely related area. About the Department The Masonic Cancer Center (MCC) is an NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting-edge research opportunities; and outstanding advanced education. Benefits Working at the UniversityAt the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.The University also offers a comprehensive benefits package that includes: |
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