Associate Director/ Principal Scientist Cell Line Engineering - Spring House Pennsylvania

Company: Disability Solutions
Location: Spring House, Pennsylvania
Posted On: 05/03/2024

At the Johnson & Johnson Innovative Medicines, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. The Cell Engineering & Analytical Sciences group within biologics development is seeking a highly skilled and motivated cell and genome engineering senior level researcher to join our research and development team. You will play a crucial role in understanding and mapping cellular protein synthesis and degradation pathways and executing and implementing paradigm shifting platform for the development of high expressing production cell lines for non-natural amino acid containing proteins. This is a hands-on leadership role with the potentiality to lead a team of 3-4 researchers. We work in an exciting, interdisciplinary environment and collaborate with multi-functional teams, including biologics discovery, cell line development, analytical sciences and cell culture process development. Your expertise in cell and genome engineering will help drive the advancement of our biopharmaceutical pipeline and provide you with the opportunity to learn and grow through your interactions with experts in a wide variety of disciplines. Key Responsibilities:

• An experienced and hands-on leader to lead a core team to develop non-natural amino acid expression technologies, utilizing cutting edge cell engineering concepts and techniques
• Versatility in cell and genome engineering with proven track record of success
• Experience with developing assay systems to screen the right cell phenotype for nnAA based platform
• Drive improvements in product quantity and quality through innovative metabolic pathway engineering in manufacturing cell lines
• Interface with CLD workstream and team for seamless translation of technology development work for pipeline application
• Knows the technological and IP landscape of biomanufacturing to drive near and long term value creation
• Effective people manager with experience running a high performing team
• Prepare and present scientific findings and recommendations to internal stakeholders, project teams, and senior management. More...

      

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