Principal Scientist, Immunopeptidomics & Proteomics - Cambridge Massachusetts

Company: Disability Solutions
Location: Cambridge, Massachusetts
Posted On: 05/04/2024

Johnson and Johnson is recruiting for a Principal Scientist, Immunopeptidomics & Proteomics for our site located in Cambridge, MA. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at Do you want to use your hard-earned skills and drive to make a difference in the lives of patients? This candidate will join the growing Discovery Proteomic Platforms (DPP) group within the Discovery Technologies and Molecular Pharmacology (DTMP) department of Therapeutics Discovery to apply groundbreaking approaches to proteomic and immunopeptidomic analysis. Lead a motivated team dedicated to deploying groundbreaking mass spectrometry proteomics technologies to optimize biologic therapeutics and identify translatable biomarkers from the lab to the clinic. Support the identification and development of small and large molecule therapeutics for diseases within Oncology, Immunology, and Neuroscience. Work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline. With your help, we will drive development of medicines for our patients! Primary responsibilities: --- Manage a team of wet lab scientists enabling proteomic insights across a wide variety of programs and therapeutic modalities. --- Plan, oversee and perform wet lab proteomic activities for immunogenicity assessment, therapeutic optimization, and biomarker discovery. --- Design and apply high efficiency automation centric proteomics sample preparation methodologies across many experiment types (global proteomic profiling, immunoprecipitation, affinity, PTM analysis). --- Collaborate with bioinformatics, biologics discovery, chemistry, and safety to drive experiments across the drug discovery portfolio. --- Demonstrate creativity and apply novel approaches to solving scientific problems. Propose novel and practical ideas, aligned with scientific strategies and demands. More...

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