Associate Director, IBD/GI Research - Boston Massachusetts

Company: Initial Therapeutics, Inc.
Location: Boston, Massachusetts
Posted On: 05/05/2025

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAt Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.OBJECTIVES:The Associate Director, IBD/GI Research, Drug Discovery working in the Gastroenterology Drug Discovery Unit (GIDDU) will within a highly-functional team focused on the discovery and development of novel drug candidates for the treatment of chronic fibroinflammatory diseases.She/he will be a scientific leader with deep subject-matter expertise and will apply this expertise to lead and/or support the execution of in vivo and in vitro studies to generate key data for evaluating mechanism of action and/or drug candidate efficacy and pharmacodynamics. He/she will be responsible for managing a team of research scientists bringing novel drug candidates with high potential for anti-inflammatory and/or anti-fibrotic efficacy in humans into the early stage pipeline. She/he will need to be a highly collaborative and energetic scientist with superior communication skills, who can lead a lab-based team running multiple projects, act as senior scientific leader and/or lead early-stage matrix project teams.ACCOUNTABILITIES:

• Lead cross-functional project teams and provide technical leadership in area of expertise
• Develop and oversee novel scientific projects in a matrixed structure
• Oversee the design and execution of relevant target and drug candidate mechanism of action studies using contemporary methods and tools.
• Prepare technical reports, summaries and quantitative analyses in written and/or oral form
• Proactively identify complex obstacles to progress in specific areas; recommend and implement solutions using a diverse set of resources; regularly add value to research projects through creative ideas
• Manage a wide variety of tasks, techniques, and projects; integrate these responsibilities to produce quality results with a high level of efficiency
• Support or identify BD opportunities to enhance project progression, or functional capability expansion, with clear and specific application to needs of the liver portfolio
• Act as a scientific mentor
• Communicate with colleagues effectively
• Present data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community
• Perform as a role model supporting Takeda culture and follow policiesEDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
  • Minimum PhD degree in a scientific discipline with 7+ years experience (10 years' preferred), or
  • MS with 13+ years experience, or
  • 5 years of Industry experience required
  • 5 years of managerial experience required
  • Expertise in the design and execution of in vivo and in vitro studies for the evaluation of disease-related biology, IBD/GI and fibroinflammatory pathology
  • Deep knowledge of animal models of liver or other fibrotic diseases, and cell systems for evaluating interactions between immune cells and fibroblasts in the fibrotic niche
  • Expertise in one therapeutic modality (small molecules, antibodies & biologics, ASOs/siRNA) and familiarity with other modalities
  • Demonstrated ability to independently solve scientific problems using multiple technologies and approaches
  • Excellent oral and written communication skillsTRAVEL REQUIREMENTS:
    • The position will be based in Cambridge, MA.
    • Requires approximately 5-10% or more travel, including international travel.Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.For Location:Boston, MAU.S. Base Salary Range:The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.Locations: Boston, MAWorker Type: EmployeeWorker Sub-Type: RegularTime Type: Full timeJob Exempt: YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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