Senior Medical Director - Boston Georgia

Company: SoTalent
Location: Boston, Georgia
Posted On: 02/27/2026

Job Description Our client is seeking a senior clinical leader to join a science-led biopharmaceutical organization dedicated to advancing innovative therapies for patients with cancer. This position is based in Cambridge and plays a critical role in shaping the global clinical development strategy for oncology assets focused on solid tumors. As Senior Medical Director , you will provide end-to-end medical and scientific leadership for multiple development programs, guiding complex clinical strategies from early decision-making through late-stage development and regulatory submission. You will operate in a highly matrixed, international environment and partner closely with research, regulatory, safety, commercial, and external stakeholders. Role purpose This role carries accountability for defining and executing global clinical development strategies across major regions, including North America, Europe, and Asia. You will integrate scientific, medical, regulatory, and commercial considerations to drive informed development decisions that directly impact program viability, timelines, and patient outcomes. You will lead multidisciplinary teams through high-stakes decisions, ensuring programs are competitive, scientifically sound, and aligned with regulatory expectations. Your judgment and leadership will significantly influence portfolio success and future product availability. Key responsibilities Clinical development leadership Own the global clinical development strategy for assigned oncology programs Lead and coordinate regional development teams across multiple geographies Ensure proactive risk identification, mitigation planning, and strategic alignment across functions Continuously assess and refine development plans to reflect emerging data, regulatory guidance, and competitive landscape Strategic decision-making Review and interpret internal and external clinical data to inform major program decisions, including study design changes, advancement, or discontinuation Evaluate clinical relevance, benefit-risk profile, and positioning within current standards of care Make recommendations that may significantly affect development timelines, labeling potential, and commercial viability Study design and execution Provide oversight for protocol development, clinical study conduct, and interpretation of results Serve as a senior advisor to clinical scientists responsible for operational delivery Ensure programs remain on track through active issue management and contingency planning Medical oversight and safety Oversee medical monitoring activities, ensuring subject safety and protocol integrity Partner with pharmacovigilance teams to evaluate safety signals and overall benefit-risk profiles External engagement Lead interactions with health authorities and regulatory agencies Build and maintain relationships with external experts, investigators, and advisors Represent clinical development in high-level scientific and regulatory discussions Business development and partnerships Support evaluation of external opportunities, including in-licensing and strategic alliances Lead clinical due diligence activities and assess development feasibility and strategic fit Act as the clinical interface for active partnerships, ensuring alignment and productive collaboration Organizational leadership Contribute clinical expertise to enterprise-wide initiatives and priority task forces Collaborate with research and commercial teams to align development with scientific innovation and market needs Recruit, mentor, and develop high-performing clinical leaders and scientists Drive performance management, goal setting, and talent development within the team Qualifications and experience Education & background MD or internationally recognized equivalent Minimum of 7 years of clinical research experience across industry, CROs, or academic clinical research Significant experience in late-phase development required Therapeutic expertise Strong background in oncology, particularly solid tumor indications Experience with immuno-oncology approaches and/or antibody-based therapies highly desirable Leadership & development experience Proven track record leading global, cross-functional clinical development teams Experience managing trials across multiple regions Regulatory submission experience (e.g., NDA, MAA) strongly preferred Core competencies Exceptional communication, influence, and negotiation skills Ability to drive alignment and decisions within complex matrix environments Strong strategic thinking combined with sound clinical judgment Cultural agility and effectiveness in multinational settings Technical knowledge Deep understanding of clinical development processes and regulatory frameworks Working knowledge of GCP, ICH guidelines, and global regulatory expectations Awareness of emerging scientific and clinical trends within oncology More...

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