Research Associate II - Brisbane California

Company: Freenome
Location: Brisbane, California
Posted On: 03/17/2026

At Freenome, we are seeking a Research Associate II to help grow the Freenome Genomics Late Stage Development team. The ideal candidate is highly analytical and detail-oriented, with a strong foundation in molecular biology and knowledge of next-generation sequencing (NGS) technologies. This person is responsible for all things related to developing and validating clinical-grade assays to measure complex, blood-based analytes (e.g., whole-genome sequencing of cfDNA). You are passionate about advancing cancer diagnostics, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer. The role reports to the Manager of Genomics Late Stage Development. This role will be an onsite role based in our Brisbane, California headquarters. What you’ll do: Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approaches. Characterize automated assays by generating and analyzing experimental data. Create and manipulate high impact assay inputs, including samples and reagents formulation as required. Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments. Collaborate with development team and computational biologists, analyze data and generate study conclusions. Collaborate with clinical laboratory members to transition development protocols into production, including automation, validation experiments, and SOP development. Present data in cross functional teams. Contribute to study protocols and reports. Must haves: Bachelors with 2 years of relevant industry experience or Masters in molecular biology, or a related field. Hands-on experience in NGS based assay development including sample preparation, library preparation, target capture, and sequencing. Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers. Biological understanding of human cell-free nucleic acids and/or cancer biology. High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required. Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities. Ability to manual pipette with high confidence, accuracy, and precision. Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines. Nice to haves: Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development). Experience using ELN (electronic lab notebook) and LIMS (lab information management system). Familiarity with programing in a scientific programming language (e.g., Python or R). Benefits and additional information: The US target range of our hourly rate for new hires is $37.68 - $51.92. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. More...

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