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Co-Op, Cell Therapy CAR Screening - Spring House Pennsylvania
Company: Disability Solutions
Location: Spring House, Pennsylvania
Posted On: 05/16/2024
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/. Johnson & Johnson Innovative Medicine is recruiting for a Co-op, Cell Therapy CAR Screening and Lead Selection within the Cell Therapy Platform and Discovery Research Team for our site in Spring House, PA. At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat, and cure diseases inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies. The Cell Therapy Platform and Discovery Research Team within the Therapeutics Discovery (TD) division of J&J Innovative Medicine undertakes research and development of Chimeric Antigen Receptor (CAR)-directed cell therapies. The Cell Therapy CAR Screening and Lead Selection Team is responsible for the discovery and optimization of CAR designs to deliver highly efficacious autologous and allogeneic CAR T cell therapy products. In this position, the co-op will have the opportunity to contribute to the cutting-edge field of CAR T cell therapy and work closely with a highly skilled scientist on CAR T cell manufacturing to support therapeutic programs across hematological and solid tumors. The candidate will play a vital part in the generation, development, and optimization of CAR T cell processes. They will gain hands-on experience working with both alpha-beta (ab) T cells and gamma-delta (gd) T cells, as well as investigate various methods to enable high-throughput CAR T-cells generation. The research will focus on the identification of the most promising CAR design candidates for cell therapy applications. The co-op student will: - Collaborate closely with a scientist on CAR T cell generation process development and optimization.
- Assist in testing various methods, such as viral-based immune cell engineering to facilitate high-throughput CAR T cell manufacturing.
- Troubleshoot technical difficulties encountered during experiments.
- Work with ab and gd T cells, conducting experiments to evaluate the performance of different CAR designs.
- Conduct data analysis, interpretation, and presentation using relevant software tools such as Microsoft Office, GraphPad PRISM, FlowJo and others.
- Document detailed experimental procedures, results, and observations in electronic laboratory notebooks (ELN) to maintain accurate records.
- Foster collaborative teamwork by actively participating in lab meetings, sharing ideas, and contributing to the optimization of laboratory protocols and techniques.
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